Recombinant Rat Hmox1, His-tagged

Cat.No. : Hmox1-31R
Product Overview : Recombinant Rat Hmox1, fused with His tag, was expressed in E. coli.
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Species : Rat
Source : E.coli
Tag : His
Description : Heme-oxygenase is a ubiquitous enzyme that catalyzes the initial and rate-limiting steps in heme catabolism yielding equimolar amounts of biliverdin, iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin and the free iron is sequestered to ferritin. These products have important physiological effects as carbon monoxide is a potent vasodilator; biliverdin and bilirubin are potent antioxidants; and the free iron increases oxidative stress and regulates the expression of many mRNAs.There are three isoforms of heme-oxygenase, HO-1, HO-2 and HO-3; however HO-1 and HO-2 are the major isoforms as they both have been identified in mammals.
Form : 50mM Tris/HCl pH7.5, 5mM Bme, 0.15NaCl, 10% glycerol
Molecular Mass : ~32kDa
Purity : >90% pure by SDS - PAGE analysis.
Storage : -20°C; 1 year+ Avoid freeze/ thaw cycle.
Gene Name Hmox1 heme oxygenase (decycling) 1 [ Rattus norvegicus ]
Official Symbol Hmox1
Synonyms HMOX1; heme oxygenase (decycling) 1; heme oxygenase 1; heme oxygenase (decyclizing) 1; Ho1; Heox; Hmox; Ho-1; HEOXG; hsp32;
Gene ID 24451
mRNA Refseq NM_012580
Protein Refseq NP_036712
Pathway Heme degradation, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Keap1-Nrf2, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem;
Function enzyme binding; heme binding; heme binding; heme oxygenase (decyclizing) activity; heme oxygenase (decyclizing) activity; heme oxygenase (decyclizing) activity; heme oxygenase (decyclizing) activity; metal ion binding; oxidoreductase activity; phospholipase D activity; protein binding; protein homodimerization activity; protein homodimerization activity; signal transducer activity; signal transducer activity;

Not For Human Consumption!

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