Recombinant Rat Fgfr2 Protein, His-tagged

• Cat.No.: Fgfr2-1501R
• Product Overview: Recombinant Rat Fgfr2 Protein (Arg41-Ala285) with N-His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: Arg41-Ala285
• Description: Enables fibroblast growth factor binding activity and fibroblast growth factor-activated receptor activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to retinoic acid; and positive regulation of smooth muscle cell proliferation. Located in cell surface; cytoplasm; and nucleus. Used to study prostate cancer and retinitis pigmentosa. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in several diseases, including Beare-Stevenson cutis gyrata syndrome; Jackson-Weiss syndrome; LADD syndrome; dysgerminoma; and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.0 kDa
  Accurate Molecular Mass: 34 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Fgfr2 fibroblast growth factor receptor 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Fgfr2
• Synonyms: FGFR2; fibroblast growth factor receptor 2
• Gene ID: 25022
• mRNA Refseq: NM_001109892
• Protein Refseq: NP_001103362
• UniProt ID: Q63240