Recombinant Rat Atxn1 Protein (Thr543-Ile781), N-His tagged

• Cat.No.: Atxn1-6853R
• Product Overview: Recombinant Rattus norvegicusATX1 (Thr543-Ile781) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: Thr543-Ile781
• Description: Predicted to enable several functions, including identical protein binding activity; protein C-terminus binding activity; and single-stranded RNA binding activity. Predicted to be involved in several processes, including learning or memory; negative regulation of transcription by RNA polymerase II; and social behavior. Predicted to act upstream of or within several processes, including negative regulation of insulin-like growth factor receptor signaling pathway; positive regulation of glial cell proliferation; and visual learning. Predicted to be located in cytosol; nuclear inclusion body; and nuclear lumen. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog (s) of this gene implicated in spinocerebellar ataxia type 1. Orthologous to human ATXN1 (ataxin 1).
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 28.55 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Atxn1 ataxin 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Atxn1
• Synonyms: Atxn1; ataxin 1; Sca1; ataxin-1; spinocerebellar ataxia 1; spinocerebellar ataxia type 1 protein homolog
• Gene ID: 25049
• mRNA Refseq: NM_012726
• Protein Refseq: NP_036858
• UniProt ID: Q63540