Recombinant Pig FGB Protein, His-tagged

• Cat.No.: FGB-927P
• Product Overview: Recombinant Pig FGB Protein (Thr197-Gln495) with His tag was expressed in E. coli.

Specification

• Species: Pig
• Source: E.coli
• Tag: His
• Protein Length: Thr197-Gln495
• Description: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 37.9 kDa; Accurate Molecular Mass: 42 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: FGB fibrinogen beta chain [ Sus scrofa (pig) ]
• Official Symbol: FGB
• Synonyms: FGB; fibrinogen beta chain
• Gene ID: 100514354
• mRNA Refseq: NM_001244113
• Protein Refseq: NP_001231042
• UniProt ID: F1RX37