Recombinant Mouse Xdh protein, His/T7-tagged

• Cat.No.: Xdh-15M
• Product Overview: Recombinant Mouse Xdh(Phe231~Lys416) fused with His/T7 tag at N-terminal was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&T7
• Protein Length: 231-416 a.a.
• Description: This gene encodes a member of the xanthine dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein exists as two distinct enzymatic forms, either as xanthine dehydrogenase, or as xanthine oxidase, and functions in purine degradation. Additional studies also suggest a role in adipogenesis, and a function as a structural protein in milk fat droplets in the lactating mammary gland.
• Form: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Molecular Mass: 24.3kDa
• AA Sequence: FEGERVTWIQ VSTMEELLDL KAQHPDAKLV VGNTEIGIEM KFKNMLFPLI ICPAWILELT SVAHGPEGIS FGAACPLSLV ESVLADAIAT LPEQRTEVFR GVMEQLRWFA GKQVKSVASI GGNIITASPI SDLNPVLMAS RAKLTLASRG TKRTVWMDHT FFPGYRRTLL SPEEILVSIV IPYSRK
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Xdh xanthine dehydrogenase [ Mus musculus ]
• Official Symbol: Xdh
• Synonyms: XDH; xanthine dehydrogenase; xanthine dehydrogenase/oxidase; xanthine oxidase; XO; Xor; Xox1; Xox-1
• Gene ID: 22436
• mRNA Refseq: NM_011723
• Protein Refseq: NP_035853
• UniProt ID: Q00519
• Chromosome Location: 17 E2; 17 45.25 cM
• Pathway: Caffeine metabolism, organism-specific biosystem; Caffeine metabolism, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Folic Acid Network, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: 2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; catalytic activity; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; iron-sulfur cluster binding; metal ion binding; molybdenum ion binding; molybdopterin cofactor binding; oxidoreductase activity; oxidoreductase activity, acting on CH-OH group of donors; protein binding; protein homodimerization activity; xanthine dehydrogenase activity; xanthine dehydrogenase activity; xanthine oxidase activity