Recombinant Mouse Wdr91 Protein, MYC/DDK-tagged

• Cat.No.: Wdr91-177M
• Product Overview: Purified recombinant protein of full-length mouse WD repeat domain 91 (Wdr91), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 83.4 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Wdr91 WD repeat domain 91 [ Mus musculus (house mouse) ]
• Official Symbol: Wdr91
• Synonyms: Wdr91; WD repeat domain 91; AI987683; AU018665; 9530020G05Rik; WD repeat-containing protein 91
• Gene ID: 101240
• mRNA Refseq: NM_001013366
• Protein Refseq: NP_001013384
• UniProt ID: Q7TMQ7