Recombinant Mouse Vps39 Protein, Myc/DDK-tagged

• Cat.No.: Vps39-6941M
• Product Overview: Purified recombinant protein of Mouse VPS39 HOPS complex subunit (Vps39), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: May play a role in clustering and fusion of late endosomes and lysosomes. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription.
• Molecular Mass: 101.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vps39 VPS39 HOPS complex subunit [ Mus musculus (house mouse) ]
• Official Symbol: Vps39
• Synonyms: VPS39; vacuolar protein sorting 39 (yeast); vam6/Vps39-like protein; Vam6; Vam6P; mVam6; AW743070; A230065P22Rik
• Gene ID: 269338
• mRNA Refseq: NM_178851
• Protein Refseq: NP_849182
• UniProt ID: Q8R5L3