Recombinant Mouse Ube2a Protein, Myc/DDK-tagged
Cat.No. : | Ube2a-6779M |
Product Overview : | Purified recombinant protein of mouse full-length ubiquitin-conjugating enzyme E2A (Ube2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. |
Molecular Mass : | 17.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Ube2a ubiquitin-conjugating enzyme E2A [ Mus musculus (house mouse) ] |
Official Symbol | Ube2a |
Synonyms | UBE2A; ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae); ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; ubiquitin-protein ligase A; ubiquitin carrier protein A; ubiquitin-conjugating enzyme HR6A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); HR6A; HHR6A; Mhr6a |
Gene ID | 22209 |
mRNA Refseq | NM_019668 |
Protein Refseq | NP_062642 |
UniProt ID | Q9Z255 |
◆ Recombinant Proteins | ||
UBE2A-5053R | Recombinant Rhesus monkey UBE2A Protein, His-tagged | +Inquiry |
UBE2A-849H | Recombinant Human UBE2A protein, His-tagged | +Inquiry |
UBE2A-3359M | Recombinant Mouse UBE2A protein, His-tagged | +Inquiry |
UBE2A-6428C | Recombinant Chicken UBE2A | +Inquiry |
UBE2A-642H | Active Recombinant Human UBE2A Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
UBE2A-594HCL | Recombinant Human UBE2A 293 Cell Lysate | +Inquiry |
UBE2A-595HCL | Recombinant Human UBE2A 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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