Recombinant Mouse Trafd1 Protein, Myc/DDK-tagged

• Cat.No.: Trafd1-6622M
• Product Overview: Purified recombinant protein of mouse full-length TRAF type zinc finger domain containing 1 (Trafd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
• Molecular Mass: 63.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Trafd1 TRAF type zinc finger domain containing 1 [ Mus musculus (house mouse) ]
• Official Symbol: Trafd1
• Synonyms: TRAFD1; TRAF type zinc finger domain containing 1; TRAF-type zinc finger domain-containing protein 1; FLN29 gene product; Fln29; 1110008K06Rik
• Gene ID: 231712
• mRNA Refseq: NM_172275
• Protein Refseq: NP_758479
• UniProt ID: Q3UDK1