Recombinant Mouse Tnfsf9, FLAG-tagged

• Cat.No.: Tnfsf9-2099M
• Product Overview: Recombinant Mouse Tnfsf9 is produced inHEK 293 Cells. The extracellular domain of mouse CD137L (aa 104-309) is fused at the N-terminus to a FLAG-tag. MW= 40kDa.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 104-309 a.a.
• Description: CD137 is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), 4-1BB and induced by lymphocyte activation (ILA). The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
• Purity: ≥90% (SDS-PAGE).
• Concentration: 0.1mg/ml after reconstitution.
• Formulation: Lyophillized. Contains PBS.
• Reconstitution: Reconstitute with 100µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum.
• Specificity: Binds to mouse CD137 (4-1BB).
• Storage And Stability: Stable for at least 6 months after receipt when stored at -20°C. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

Gene Information

• Gene Name: Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 [ Mus musculus ]
• Synonyms: Tnfsf9; tumor necrosis factor (ligand) superfamily, member 9; Ly63l; 4-1BBL; Cd137l; 4-1BB-L; AI848817; tumor necrosis factor ligand superfamily member 9; 4-1BB ligand
• Gene ID: 21950
• mRNA Refseq: NM_009404
• Protein Refseq: NP_033430
• UniProt ID: P41274
• Chromosome Location: 17 D
• Pathway: Cytokine-cytokine receptor interaction
• Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding