Recombinant Mouse Tgfbr1 Protein, Myc/DDK-tagged

• Cat.No.: Tgfbr1-6392M
• Product Overview: Purified recombinant protein of mouse full-length transforming growth factor, beta receptor I (Tgfbr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
• Molecular Mass: 56.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tgfbr1 transforming growth factor, beta receptor I [ Mus musculus (house mouse) ]
• Official Symbol: Tgfbr1
• Synonyms: TGFBR1; transforming growth factor, beta receptor I; TGF-beta receptor type-1; ESK2; TGFR-1; TGF-beta receptor type I; transforming growth factor-beta receptor type I; ALK5; Alk-5; TbetaRI; AU017191; TbetaR-I
• Gene ID: 21812
• mRNA Refseq: NM_009370
• Protein Refseq: NP_033396
• UniProt ID: Q64729