Recombinant Mouse Tfip11 Protein, Myc/DDK-tagged

• Cat.No.: Tfip11-6382M
• Product Overview: Purified recombinant protein of mouse full-length tuftelin interacting protein 11 (Tfip11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 96.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tfip11 tuftelin interacting protein 11 [ Mus musculus (house mouse) ]
• Official Symbol: Tfip11
• Synonyms: TFIP11; tuftelin interacting protein 11; tuftelin-interacting protein 11; STIP-1; tuftelin-interacting protein 33; tuftelin-interacting protein 39; tuftelin-interacting protein, 39 kD; septin and tuftelin-interacting protein 1; Srr1; TIP33; Tip39; AF097181; AW046167; 2810002G02Rik
• Gene ID: 54723
• mRNA Refseq: NM_018783
• Protein Refseq: NP_061253
• UniProt ID: Q9ERA6