Recombinant Mouse Stim1 Protein, Myc/DDK-tagged

• Cat.No.: Stim1-6179M
• Product Overview: Purified recombinant protein of mouse full-length stromal interaction molecule 1 (Stim1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.
• Molecular Mass: 77.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Stim1 stromal interaction molecule 1 [ Mus musculus (house mouse) ]
• Official Symbol: Stim1
• Synonyms: STIM1; stromal interaction molecule 1; SIM
• Gene ID: 20866
• mRNA Refseq: NM_009287
• Protein Refseq: NP_033313
• UniProt ID: P70302