Recombinant Mouse Smad2 Protein, Myc/DDK-tagged
Cat.No. : | Smad2-5950M |
Product Overview : | Purified recombinant protein of mouse full-length SMAD family member 2 (Smad2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. |
Molecular Mass : | 52.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Smad2 SMAD family member 2 [ Mus musculus (house mouse) ] |
Official Symbol | Smad2 |
Synonyms | SMAD2; MAD homolog 2 (Drosophila); mothers against decapentaplegic homolog 2; Smad 2; SMAD family member 2; mad-related protein 2; mothers against DPP homolog 2; Madh2; Madr2; mMad2; Smad-2; 7120426M23Rik |
Gene ID | 17126 |
mRNA Refseq | NM_010754 |
Protein Refseq | NP_034884 |
UniProt ID | Q62432 |
◆ Recombinant Proteins | ||
SMAD2-6130C | Recombinant Chicken SMAD2 | +Inquiry |
SMAD2-392H | Recombinant Human SMAD Family Member 2, His-tagged | +Inquiry |
SMAD2-4039H | Recombinant Human SMAD2 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
SMAD2-6129H | Recombinant Human SMAD2 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
SMAD2-350HFL | Active Recombinant Full Length Human SMAD2 Protein, C-Flag-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
SMAD2-001MCL | Recombinant Mouse SMAD2 cell lysate | +Inquiry |
Not For Human Consumption!
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