Recombinant Mouse Slit2 Protein, Myc/DDK-tagged

• Cat.No.: Slit2-5944M
• Product Overview: Purified recombinant protein of mouse full-length slit guidance ligand 2 (Slit2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the Slit family of secreted glycoproteins, which function as ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. In mammals, members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Mice deficient for this gene exhibit abnormal axonal projections in the embryonic forebrain and develop supernumerary uretic buds that maintain improper connections to the nephric duct. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 169.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slit2 slit guidance ligand 2 [ Mus musculus (house mouse) ]
• Official Symbol: Slit2
• Synonyms: Slit2; slit guidance ligand 2; S; Drad; Slil3; Drad-1; slit-2; mKIAA4141; b2b1200.1Clo; E030015M03Rik; E130320P19Rik; slit homolog 2 protein; downregulated during adipocyte differentiation-1; neurogenic extracellular slit protein
• Gene ID: 20563
• mRNA Refseq: NM_178804
• Protein Refseq: NP_848919
• UniProt ID: Q9R1B9