Recombinant Mouse Sirpa Protein (Lys32-Leu146), Fc tagged

• Cat.No.: Sirpa-6805M
• Product Overview: Recombinant mouse Sirpa (Lys32-Leu146) fused with the Fc tag was expressed in mammalian cells.

Specification

• Description: Enables protein phosphatase binding activity and protein phosphorylated amino acid binding activity. Involved in several processes, including negative regulation of MAPK cascade; negative regulation of cytokine production; and negative regulation of nitrogen compound metabolic process. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; phagocytosis; and positive regulation of phagocytosis. Is integral component of plasma membrane. Is expressed in several structures, including adrenal gland; cartilage; central nervous system; genitourinary system; and retina. Orthologous to several human genes including SIRPA (signal regulatory protein alpha).
• Source: Mammalian cells
• Species: Mouse
• Tag: Fc
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 45.67 kDa
• Protein length: Lys32-Leu146
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Sirpa signal-regulatory protein alpha [ Mus musculus (house mouse) ]
  Gene ID: 19261, updated on 6-Oct-2023
  Download Datasets
  Summary
  Official Symbol
  Sirpaprovided by MGI
  Official Full Name
  signal-regulatory protein alphaprovided by MGI
  Primary source
  MGI:MGI:108563
  See related
  Ensembl:ENSMUSG00000037902 AllianceGenome:MGI:108563
  Gene type
  protein coding
  RefSeq status
  VALIDATED
  Organism
  Mus musculus
  Lineage
  Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
  Also known as
  Bit; P84; SIRP; SHP-1; CD172a; Ptpns1; SHPS-1; Idd13.2
• Official Symbol: Sirpa
• Synonyms: Sirpa; signal-regulatory protein alpha; Bit; P84; SIRP; SHP-1; CD172a; Ptpns1; SHPS-1; Idd13.2; tyrosine-protein phosphatase non-receptor type substrate 1; CD172 antigen-like family member A; SHP substrate 1; brain Ig-like molecule with tyrosine-based activation motifs; brain immunological-like with tyrosine-based motifs; inhibitory receptor SHPS-1; mSIRP-alpha1; myD-1 antigen; protein tyrosine phosphatase, non-receptor type substrate 1; signal-regulatory protein alpha-1; sirp-alpha-1; EC 3.1.3.48
• Gene ID: 19261
• mRNA Refseq: NM_001177647
• Protein Refseq: NP_001171118
• UniProt ID: P97797