Recombinant Mouse Rtn4 Protein, Myc/DDK-tagged

• Cat.No.: Rtn4-5643M
• Product Overview: Purified recombinant protein of mouse full-length reticulon 4 (cDNA clone MGC:38204 IMAGE:5323152), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities.
• Molecular Mass: 70.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rtn4 reticulon 4 [ Mus musculus (house mouse) ]
• Official Symbol: Rtn4
• Synonyms: Rtn4; reticulon 4; N; No; ASY; NgA; Nog; NOGO; NSP-CL; Nogo-A; Nogo-B; Nogo-C; AA407876; AA409940; AA960376; mKIAA0886; mKIAA4153; 1110020G17Rik; C130026I10Rik; reticulon-4; neurite outgrowth inhibitor
• Gene ID: 68585
• mRNA Refseq: NM_024226
• Protein Refseq: NP_077188
• UniProt ID: Q99P72