Recombinant Mouse Rp2 Protein, Myc/DDK-tagged

• Cat.No.: Rp2-5577M
• Product Overview: Purified recombinant protein of mouse full-length retinitis pigmentosa 2 homolog (Rp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
• Molecular Mass: 39.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rp2 retinitis pigmentosa 2 homolog [ Mus musculus (house mouse) ]
• Official Symbol: Rp2
• Synonyms: Rp2; retinitis pigmentosa 2 homolog; Rp; Rp2h; AI662636; protein XRP2
• Gene ID: 19889
• mRNA Refseq: NM_133669
• Protein Refseq: NP_598430
• UniProt ID: Q9EPK2