Recombinant Mouse Rheb Protein, Myc/DDK-tagged

• Cat.No.: Rheb-5504M
• Product Overview: Purified recombinant protein of mouse full-length Ras homolog enriched in brain (Rheb), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
• Molecular Mass: 20.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rheb Ras homolog enriched in brain [ Mus musculus (house mouse) ]
• Official Symbol: Rheb
• Synonyms: RHEB; Ras homolog enriched in brain; GTP-binding protein Rheb; RAS-homolog enriched in brain
• Gene ID: 19744
• mRNA Refseq: NM_053075
• Protein Refseq: NP_444305
• UniProt ID: Q921J2