Recombinant Mouse RGM Domain Family, Member A, FLAG-tagged

• Cat.No.: Rgma-2417M
• Product Overview: Recombinant mouse RGMA (repulsive guidance molecule A) (aa 48-423) produced inHEK 293 cellsis fused at the N-terminus to a FLAG-tag,16kDa.

Specification

• Species: Mouse
• Source: Human Cells
• Tag: Flag
• Protein Length: 48-423 a.a.
• Description: Repulsive guidance molecule A also known as RGMa is a protein that in humans is encoded by the RGMA gene. RGMa is a repulsive guidance molecule for retinal axons.Furthermore neogenin functions as a receptor for RGM.Neogenin overexpression and RGM downexpression in the developing embryonic neural tube induces apoptosis. The apoptotic activity of neogenin in the neural tube is associated with cleavage of its cytoplasmic domain by caspases.
• Source/Host: HEK 293 cells.
• Concentration: 0.1mg/ml after reconstitution.
• Purity: ≥95% (SDS-PAGE).
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
• Short Term Storage: +4°C.
• Formulation: Lyophilized. Contains PBS.
• Long Term Storage: -20°C.
• Use/Stability: Stable for at least 6 months after receipt when stored at -20°C.
• Handling: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Rgma RGM domain family, member A [ Mus musculus ]
• Synonyms: RGM domain family, member A; BC059072; MGC38550; MGC69915; C230063O06; Rgma; repulsive guidance molecule A
• Gene ID: 244058
• mRNA Refseq: NM_177740
• Protein Refseq: NP_808408
• UniProt ID: Q6PCX7
• Chromosome Location: 7 D1
• Function: molecular_function