Recombinant Mouse Retn, FLAG-tagged

• Cat.No.: Retn-476M
• Product Overview: Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 21-114 a.a.
• Description: The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
• Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
• Molecular Mass: ~15kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Applications: Has been shown to be a fully-functional ligand for decorin [1].
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 0.4mg/ml

Gene Information

• Gene Name: Retn resistin [ Mus musculus ]
• Official Symbol: Retn
• Synonyms: RETN; resistin; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; dominant inhibitory adipocyte-specific secretory factor; adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; Rstn; Xcp4; Fizz3
• Gene ID: 57264
• mRNA Refseq: NM_001204959
• Protein Refseq: NP_001191888
• Pathway: Adipogenesis, organism-specific biosystem
• Function: hormone activity