Recombinant Mouse Prdx6 Protein, MYC/DDK-tagged

• Cat.No.: Prdx6-612M
• Product Overview: Purified recombinant protein of full-length mouse peroxiredoxin 6, complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 24.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prdx6 peroxiredoxin 6 [ Mus musculus (house mouse) ]
• Official Symbol: Prdx6
• Synonyms: Prdx6; peroxiredoxin 6; GPx; Aop2; CP-3; Ltw4; Ltw-4; NSGPx; ORF06; Prdx5; Brp-12; Lvtw-4; aiPLA2; 1-cysPrx; AA690119; 1-Cys Prx; 9430088D19Rik; peroxiredoxin-6; 1-Cys peroxiredoxin; acidic calcium-independent phospholipase A2; anti-oxidant protein 2, related sequence 3; antioxidant protein 2; glutathione-dependent peroxiredoxin; non-selenium glutathione peroxidase; peroxiredoxin 5, related sequence 3; peroxiredoxin 6, related sequence 3; EC 1.11.1.27; EC 3.1.1.4
• Gene ID: 11758
• mRNA Refseq: NM_007453
• Protein Refseq: NP_031479
• UniProt ID: O08709