Recombinant Mouse Poll Protein, Myc/DDK-tagged

• Cat.No.: Poll-4992M
• Product Overview: Purified recombinant protein of mouse full-length polymerase (DNA directed), lambda (Poll), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
• Molecular Mass: 62.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Poll polymerase (DNA directed), lambda [ Mus musculus (house mouse) ]
• Official Symbol: Poll
• Synonyms: POLL; polymerase (DNA directed), lambda; DNA polymerase lambda; pol Lambda; DNA polymerase kappa; AV007317; 1110003P06Rik
• Gene ID: 56626
• mRNA Refseq: NM_020032
• Protein Refseq: NP_064416
• UniProt ID: Q9QXE2