Recombinant Mouse Pmpcb Protein, Myc/DDK-tagged

• Cat.No.: Pmpcb-4959M
• Product Overview: Purified recombinant protein of mouse full-length peptidase (mitochondrial processing) beta (Pmpcb), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis.
• Molecular Mass: 55.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pmpcb peptidase (mitochondrial processing) beta [ Mus musculus (house mouse) ]
• Official Symbol: Pmpcb
• Synonyms: PMPCB; peptidase (mitochondrial processing) beta; mitochondrial-processing peptidase subunit beta; P-52; beta-MPP; MPPB; MPP11; MPPP52; 3110004O18Rik
• Gene ID: 73078
• mRNA Refseq: NM_028431
• Protein Refseq: NP_082707
• UniProt ID: Q9CXT8