Recombinant Mouse Pgrmc1 Protein, Myc/DDK-tagged

• Cat.No.: Pgrmc1-4829M
• Product Overview: Purified recombinant protein of mouse full-length progesterone receptor membrane component 1 (Pgrmc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins.
• Molecular Mass: 22.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pgrmc1 progesterone receptor membrane component 1 [ Mus musculus (house mouse) ]
• Official Symbol: Pgrmc1
• Synonyms: Pgrmc1; progesterone receptor membrane component 1; P; Ve; mPR; HPR6; PPMR; Vema; HPR6.6; AA415812; membrane-associated progesterone receptor component 1
• Gene ID: 53328
• mRNA Refseq: NM_016783
• Protein Refseq: NP_058063
• UniProt ID: O55022