Recombinant Mouse PDGFRA Protein (Leu25-Glu524), C-His tagged

• Cat.No.: PDGFRA-6767M
• Product Overview: Recombinant mouse PDGFRA (Leu25-Glu524) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: Leu25-Glu524
• Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 55 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PDGFRA platelet derived growth factor receptor alpha [ Homo sapiens (human) ]
• Official Symbol: PDGFRA
• Synonyms: PDGFRA; platelet derived growth factor receptor alpha; CD140A; PDGFR2; PDGFR-2; platelet-derived growth factor receptor alpha; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; alpha-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor, alpha polypeptide; EC 2.7.10.1
• Gene ID: 5156
• mRNA Refseq: NM_006206
• Protein Refseq: NP_006197
• MIM: 173490
• UniProt ID: P16234