Recombinant Mouse Nxn Protein, Myc/DDK-tagged

• Cat.No.: Nxn-4562M
• Product Overview: Purified recombinant protein of mouse full-length nucleoredoxin (cDNA clone MGC:7861 IMAGE:3501314), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
• Molecular Mass: 68.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nxn nucleoredoxin [ Mus musculus (house mouse) ]
• Official Symbol: Nxn
• Synonyms: Nxn; nucleoredoxin; l11Jus; l11Jus13nucleoredoxin; protein Red-1; EC 1.8.1.8
• Gene ID: 18230
• mRNA Refseq: NM_008750
• Protein Refseq: NP_032776
• UniProt ID: P97346