Recombinant Mouse Lsm6 Protein, Myc/DDK-tagged

• Cat.No.: Lsm6-3858M
• Product Overview: Purified recombinant protein of mouse full-length LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 9.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated [ Mus musculus (house mouse) ]
• Official Symbol: Lsm6
• Synonyms: LSM6; LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm6; AI747288; 1500031N17Rik; 2410088K19Rik; MGC117708
• Gene ID: 78651
• mRNA Refseq: NM_030145
• Protein Refseq: NP_084421
• UniProt ID: P62313