Recombinant Mouse Lox Protein, MYC/DDK-tagged

• Cat.No.: Lox-1333M
• Product Overview: Purified recombinant protein of full-length mouse lysyl oxidase (Lox), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 47.2 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lox lysyl oxidase [ Mus musculus (house mouse) ]
• Official Symbol: Lox
• Synonyms: Lox; lysyl oxidase; rrg; TSC-160; AI893619; protein-lysine 6-oxidase; ras excision protein; ras recision; EC 1.4.3.13
• Gene ID: 16948
• mRNA Refseq: NM_010728
• Protein Refseq: NP_034858
• UniProt ID: P28301