Recombinant Mouse L1cam Protein, His-tagged

• Cat.No.: L1cam-1725M
• Product Overview: Recombinant Mouse L1cam Protein (Ser882-Ala1132) with N-His tag was expressed in E. coli.

Specification

• Description: Enables several functions, including identical protein binding activity; integrin binding activity; and sialic acid binding activity. Acts upstream of or within several processes, including cell-cell adhesion mediated by integrin; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and homophilic cell adhesion via plasma membrane adhesion molecules. Located in external side of plasma membrane; presynaptic membrane; and terminal bouton. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in MASA syndrome; hydrocephalus; ovarian carcinoma; pancreatic cancer; and schizophrenia. Orthologous to human L1CAM (L1 cell adhesion molecule).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.86 kDa
• Protein length: Ser882-Ala1132
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: L1cam L1 cell adhesion molecule [ Mus musculus (house mouse) ]
• Official Symbol: L1cam
• Synonyms: L1CAM; L1 cell adhesion molecule; neural cell adhesion molecule L1; L1; CD171; NCAM-L1; N-CAM-L1
• Gene ID: 16728
• mRNA Refseq: NM_008478
• Protein Refseq: NP_032504
• UniProt ID: P11627