Recombinant Mouse Irf4 Protein, Myc/DDK-tagged

• Cat.No.: Irf4-3575M
• Product Overview: Purified recombinant protein of mouse full-length interferon regulatory factor 4 (Irf4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
• Molecular Mass: 52 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Irf4 interferon regulatory factor 4 [ Mus musculus (house mouse) ]
• Official Symbol: Irf4
• Synonyms: IRF4; interferon regulatory factor 4; NF-EM5; PU.1 interaction partner; transcriptional activator PIP; Sfpi1/PU.1 interaction partner; lymphocyte-specific interferon regulatory factor; Spip; IRF-4; LSIRF; AI385587
• Gene ID: 16364
• mRNA Refseq: NM_013674
• Protein Refseq: NP_038702
• UniProt ID: Q64287