Recombinant Mouse Il23a Protein, His-tagged

• Cat.No.: Il23a-2304M
• Product Overview: Recombinant Mouse Il23a Protein (Met23-Ser335+IGSGSSRGGSGSGGSGGGGSK+Leu20-Ala196) with a N-His tag was expressed in 293F.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: Met23-Ser335+IGSGSSRGGSGSGGSGGGGSK+Leu20-Ala196
• Description: Contributes to interleukin-23 receptor binding activity. Involved in positive regulation of defense response to virus by host; positive regulation of immune response; and positive regulation of neutrophil chemotaxis. Acts upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Part of interleukin-23 complex. Is expressed in decidua; decidua basalis; embryo; and extraembryonic component. Orthologous to human IL23A (interleukin 23 subunit alpha).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 58.8 kDa
  Accurate Molecular Mass: 70 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Il23a interleukin 23, alpha subunit p19 [ Mus musculus (house mouse) ]
• Official Symbol: Il23a
• Synonyms: Il23a; interleukin 23, alpha subunit p19; p19; IL-23; interleukin-23 subunit alpha
  IL-23 subunit alpha
  IL-23-A
  IL-23p19
  interleukin-23 subunit p19
• Gene ID: 83430
• mRNA Refseq: NM_031252
• Protein Refseq: NP_112542
• UniProt ID: Q9EQ14

Q&As

Is this bioactive cyno IL-23 heterodimer (p19/p40) or just the cyno IL-23p19 subunit?

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