Recombinant Mouse IL2 Protein

• Cat.No.: IL2-79M
• Product Overview: Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed.

Specification

• Species: Mouse
• Source: E.coli
• Protein Length: 21-169 a.a.
• Description: Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.
• Form: Lyophilized from a 0.2 um filtered solution of 20mM Sodium Citrate, 5% Trehalose, pH4.5.
• AA Sequence: Ala21-Gln169
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: Il2 interleukin 2 [ Mus musculus (house mouse) ]
• Official Symbol: IL2
• Synonyms: aldesleukin; interleukin 2; interleukin-2; IL-2; T-cell growth facter; T cell growth factor; TCGF
• Gene ID: 16183
• mRNA Refseq: NM_008366.3
• Protein Refseq: NP_032392.1
• UniProt ID: P04351