Recombinant Mouse Il16 Protein, MYC/DDK-tagged

• Cat.No.: Il16-1239M
• Product Overview: Purified recombinant protein of full-length mouse interleukin 16 (Il16), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
• Molecular Mass: 141.4 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Il16 interleukin 16 [ Mus musculus (house mouse) ]
• Official Symbol: Il16
• Synonyms: Il16; interleukin 16; mKIAA4048; pro-interleukin-16
• Gene ID: 16170
• mRNA Refseq: NM_010551
• Protein Refseq: NP_034681
• UniProt ID: O54824