Recombinant Mouse Il12a Protein (Met1-Ala215, Met1-Ser335), C-His and C-TwinStrep tagged

• Cat.No.: Il12a-6736M
• Product Overview: Recombinant mouse IL12 (Met1-Ala215 & Met1-Ser335) fused with the C-terminal His Tag & C-terminal Twin-Strep Tag was expressed in mammalian cells.

Specification

• Description: Enables interleukin-12 beta subunit binding activity. Contributes to cytokine activity. Acts upstream of or within several processes, including T-helper 1 cell activation; defense response to protozoan; and positive regulation of T cell activation. Located in cell surface; cytoplasm; and extracellular space. Part of interleukin-12 complex. Is expressed in brain; lung; small intestine; testis; and thymus. Human ortholog (s) of this gene implicated in hepatitis C; hepatocellular carcinoma; and primary biliary cholangitis. Orthologous to human IL12A (interleukin 12A).
• Source: Mammalian cells
• Species: Mouse
• Tag: C-His and C-TwinStrep
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 63.2 kDa
• Protein length: Met1-Ala215, Met1-Ser335
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Il12a interleukin 12a [ Mus musculus (house mouse) ]
• Official Symbol: Il12a
• Synonyms: Il12a; interleukin 12a; p35; Ll12a; Il-12a; IL-12p35; interleukin-12 subunit alpha; CLMF p35; IL-12 p35 subunit; IL-12 subunit p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12a p35 subunit; interleukin-12 p35 subunit
• Gene ID: 16159
• mRNA Refseq: NM_001159424
• Protein Refseq: NP_001152896
• UniProt ID: P43431