Recombinant Mouse Hexa Protein, MYC/DDK-tagged

• Cat.No.: Hexa-1116M
• Product Overview: Purified recombinant protein of full-length mouse hexosaminidase A (Hexa), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mice lacking the encoded protein exhibit accumulation of gangliosides in the brain and membranous cytoplasmic bodies in neurons. Certain mutations in the human ortholog of this gene cause Tay-Sachs disease.
• Molecular Mass: 60.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hexa hexosaminidase A [ Mus musculus (house mouse) ]
• Official Symbol: Hexa
• Synonyms: Hexa; hexosaminidase A; Hex-1; beta-hexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; hexosaminidase subunit A; EC 3.2.1.52
• Gene ID: 15211
• mRNA Refseq: NM_010421
• Protein Refseq: NP_034551
• UniProt ID: P29416