Recombinant Mouse Granzyme B

• Cat.No.: Gzmb-414M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), also known as GZMB, is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. Granzyme B may be a useful prognostic marker in early rheumatoid arthritis and may provide important clues to the pathogenesis of this disease.
• Molecular Weight: The molecular weight of Recombinant Mouse Granzyme B is 34-37 kDa.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Gzmb granzyme B [ Mus musculus ]
• Synonyms: Gzmb; granzyme B; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1; C11
• Gene ID: 14939
• mRNA Refseq: NM_013542
• Protein Refseq: NP_038570
• UniProt ID: P04187
• Chromosome Location: 14
• Pathway: Allograft rejection; Autoimmune thyroid disease; Graft-versus-host disease; Natural killer cell mediated cytotoxicity; Type I diabetes mellitus
• Function: catalytic activity; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity