Recombinant Mouse Gpx3, FLAG-tagged

• Cat.No.: Gpx3-284M
• Product Overview: Mouse GPX3 (aa 1-226) is fused at the C-terminus to a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 1-226 a.a.
• Description: Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
• Form: Liquid. 0.2μm-filtered solution in PBS, pH7.2.
• Molecular Mass: ~22kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Gpx3 glutathione peroxidase 3 [ Mus musculus ]
• Official Symbol: Gpx3
• Synonyms: GPX3; glutathione peroxidase 3; GPx-3; GPx-P; plasma GPx; extracellular GPx; plasma glutathione peroxidase; GPx; EGPx; GSHPx-3; GSHPx-P; AA960521
• Gene ID: 14778
• mRNA Refseq: NM_008161
• Protein Refseq: NP_032187
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folic Acid Network, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; One carbon metabolism and related pathways, organism-specific biosystem
• Function: glutathione binding; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity; peroxidase activity; selenium binding