Recombinant Mouse Git1 Protein, Myc/DDK-tagged

• Cat.No.: Git1-3215M
• Product Overview: Purified recombinant protein of mouse full-length GIT ArfGAP 1 (Git1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve ENTR1 and PTPN13.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 85.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Git1 GIT ArfGAP 1 [ Mus musculus (house mouse) ]
• Official Symbol: Git1
• Synonyms: GIT1; G protein-coupled receptor kinase-interactor 1; ARF GTPase-activating protein GIT1; ARF GAP GIT1; GRK-interacting protein 1; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein; Cat-1; p95Cat
• Gene ID: 216963
• mRNA Refseq: NM_001004144
• Protein Refseq: NP_001004144
• UniProt ID: Q68FF6