Recombinant Mouse Gdf2 protein, His-tagged

• Cat.No.: Gdf2-1852M
• Product Overview: Recombinant Mouse Gdf2 aa. (Ile241~Glu418 (Accession # Q9WV56)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Ile241~Glu418
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.3kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Gdf2 growth differentiation factor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Gdf2
• Synonyms: Gdf2; growth differentiation factor 2; Bmp9; growth/differentiation factor 2; bone morphogenetic protein 9
• Gene ID: 12165
• mRNA Refseq: NM_019506.4
• Protein Refseq: NP_062379.3
• UniProt ID: Q9WV56