Recombinant Mouse Gck Protein, MYC/DDK-tagged

• Cat.No.: Gck-245M
• Product Overview: Purified recombinant protein of full-length mouse glucokinase (cDNA clone MGC:18414 IMAGE:4195943), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
• Molecular Mass: 51.9 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gck glucokinase [ Mus musculus (house mouse) ]
• Official Symbol: Gck
• Synonyms: Gck; glucokinase; Gk; GLK; HK4; HKIV; HXKP; Hlb62; MODY2; Gls006; hexokinase-4; HK IV; hexokinase type IV; hexokinase-D; EC 2.7.1.1
• Gene ID: 103988
• mRNA Refseq: NM_010292
• Protein Refseq: NP_034422
• UniProt ID: P52792