Recombinant Mouse Fos Protein, His-tagged

• Cat.No.: Fos-940M
• Product Overview: Recombinant Mouse Fos Protein (Val55-Phe298) with His tag was expressed in 293F.

Specification

• Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including positive regulation of osteoclast differentiation; response to muscle stretch; and skeletal muscle cell differentiation. Located in endoplasmic reticulum and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit).
• Source: HEK293F
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.2 kDa; Accurate Molecular Mass: \
• Protein length: Val55-Phe298
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Fos FBJ osteosarcoma oncogene [ Mus musculus (house mouse) ]
• Official Symbol: Fos
• Synonyms: FOS; FBJ osteosarcoma oncogene; proto-oncogene c-Fos; cellular oncogene fos; proto-oncogene protein c-fos; cFos; c-fos; D12Rfj1
• Gene ID: 14281
• mRNA Refseq: NM_010234
• Protein Refseq: NP_034364
• UniProt ID: P01101