Recombinant Mouse Fnta Protein, Myc/DDK-tagged

• Cat.No.: Fnta-3067M
• Product Overview: Purified recombinant protein of mouse full-length farnesyltransferase, CAAX box, alpha (Fnta), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 44 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fnta farnesyltransferase, CAAX box, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Fnta
• Synonyms: FNTA; farnesyltransferase, CAAX box, alpha; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FTase-alpha; GGTase-I-alpha; CAAX farnesyltransferase subunit alpha; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase subunit alpha; FTA
• Gene ID: 14272
• mRNA Refseq: NM_008033
• Protein Refseq: NP_032059
• UniProt ID: Q61239