Recombinant Mouse Fndc4 Protein, Myc/DDK-tagged

• Cat.No.: Fndc4-3064M
• Product Overview: Purified recombinant protein of mouse full-length fibronectin type III domain containing 4 (Fndc4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
• Molecular Mass: 25.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fndc4 fibronectin type III domain containing 4 [ Mus musculus (house mouse) ]
• Official Symbol: Fndc4
• Synonyms: FNDC4; fibronectin type III domain containing 4; fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; fibronectin type III repeat-containing protein 1; FRCP1; Fnmp1; AB030187; AI838506; AW487863; 2810430J06Rik; 6330410H20Rik
• Gene ID: 64339
• mRNA Refseq: NM_022424
• Protein Refseq: NP_071869
• UniProt ID: Q3TR08