Recombinant Mouse Fkbp1a, His-tagged

• Cat.No.: Fkbp1a-64M
• Product Overview: Recombinant mouse Fkbp1a, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: Fkbp1a also known as peptidyl-prolyl cis-trans isomerase FKBP1A belongs to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Fkbp1a also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1, 4, 5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor.
• Form: Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT
• Molecular Mass: 14.4kDa (132aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGVQVE TISPGDGRTF PKRGQTCVVH YTGMLEDGKK FDSSRDRNKP FKFTLGKQEV IRGWEEGVAQ MSVGQRAKLI ISSDYAYGAT GHPGIIPPHA TLVFDVELLK LE
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Fkbp1a FK506 binding protein 1a [ Mus musculus ]
• Official Symbol: Fkbp1a
• Synonyms: FKBP1A; FK506 binding protein 1a; peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; FKBP-1A; rotamase; 12 kDa FKBP; calstabin-1; FKBP12-Exip3; PPIase FKBP1A; immunophilin FKBP12; FK506 binding protein12; FK506-binding protein 1A; FK506 Binding Protein12-T1; FK506 binding protein12-T2; 12 kDa FK506-binding protein; Fkbp; 12kDa; Fkbp1; FKBP12; mFKBP1; mFKBP12; FKBP12-T1; FKBP12-T2
• Gene ID: 14225
• mRNA Refseq: NM_008019
• Protein Refseq: NP_032045
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem
• Function: FK506 binding; FK506 binding; FK506 binding; Hsp70 protein binding; SMAD binding; activin binding; drug binding; enzyme binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding; signal transducer activity; transforming growth factor beta receptor binding; type I transforming growth factor beta receptor binding