Recombinant Mouse Fig4 Protein, MYC/DDK-tagged

• Cat.No.: Fig4-226M
• Product Overview: Purified recombinant protein of full-length mouse FIG4 phosphoinositide 5-phosphatase (Fig4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 103.4 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fig4 FIG4 phosphoinositide 5-phosphatase [ Mus musculus (house mouse) ]
• Official Symbol: Fig4
• Synonyms: Fig4; FIG4 phosphoinositide 5-phosphatase; Sac3; AI326867; A530089I17Rik; polyphosphoinositide phosphatase; FIG4 homolog; SAC domain-containing protein 3; Sac domain-containing inositol phosphatase 3; phosphatidylinositol 3,5-bisphosphate 5-phosphatase
• Gene ID: 103199
• mRNA Refseq: NM_133999
• Protein Refseq: NP_598760
• UniProt ID: Q91WF7