Recombinant Mouse Fatty Acid Binding Protein 4, Adipocyte, His-tagged

• Cat.No.: Fabp4-1004M
• Product Overview: Recombinant Mouse Fabp4 was produced inE.Colifused with a his tag.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: Fatty-acid binding protein 4(FABP4), also termed adipocyte fatty-acid binding protein (A-FABP), or aP2, is a novel adipocyte-expressed factor which accounted for ~6% of total cellular proteins. Several animal experiments suggested that FABP-4 plays a key role in the link between obesity and various features of metabolic syndrome. Mice with targeted disruption of FABP-4 accompany FABP-5 almost completely protect against diet-induced obesity, insulin resistance, dyslipidemia, type 2 diabetes, and fatty liver disease. Studies in human found FABP-4 serum levels were significantly increased in overweight and obese subjects, which predicted the risk to develop metabolic syndrome and type 2 diabetes. Additionally, serum FABP-4 levels were associated with carotid atherosclerosis and coronary artery disease.
• Amino Acid Sequence: MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDLV TIRSESTFKN TEISFKLGVE FDEITADDRK VKSIITLDGG ALVQVQKWDG KSTTIKRKRD GDKLVVECVM KGVTSTRVYE RA
• Form: Filtered (0.22 μm) and lyophilized in 1 mg/mL in PBS.
• Purity: >95%.
• Applications: ELISA, Western blotting, Immunoprecipitation
• Reconstitution: Add deionized water to prepare a working stock solution of approximately 1 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Storage: Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing /thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Gene Information

• Gene Name: Fabp4 fatty acid binding protein 4, adipocyte [ Mus musculus ]
• Synonyms: Fabp4; fatty acid binding protein 4, adipocyte; Ap2; Lbpl; 422/aP2; ALBP/Ap2; adipocyte protein aP2; lipid binding protein-like
• Gene ID: 11770
• mRNA Refseq: NM_024406
• Protein Refseq: NP_077717
• UniProt ID: P04117
• Chromosome Location: 313.9 cM
• Pathway: PPAR signaling pathway
• Function: Binding; lipid binding; transcription repressor activity; transporter activity