Recombinant Mouse Faap24 Protein, MYC/DDK-tagged

• Cat.No.: Faap24-192M
• Product Overview: Purified recombinant protein of full-length mouse Fanconi anemia core complex associated protein 24 (Faap24), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
• Molecular Mass: 25.1 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Faap24 Fanconi anemia core complex associated protein 24 [ Mus musculus (house mouse) ]
• Official Symbol: Faap24
• Synonyms: Faap24; Fanconi anemia core complex associated protein 24; AW124591; AW538696; C230052I12Rik; Fanconi anemia core complex-associated protein 24; Fanconi anemia-associated protein, 24 kDa; fanconi anemia-associated protein of 24 kDa
• Gene ID: 101831
• mRNA Refseq: NM_178643
• Protein Refseq: NP_848758
• UniProt ID: Q8BHL6