Recombinant Mouse F3 Protein, MYC/DDK-tagged

• Cat.No.: F3-999M
• Product Overview: Purified recombinant protein of full-length mouse coagulation factor III (F3), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis.
• Molecular Mass: 32.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: F3 coagulation factor III [ Mus musculus (house mouse) ]
• Official Symbol: F3
• Synonyms: F3; coagulation factor III; TF; Cf3; Cf-3; CD142; AA409063; tissue factor
• Gene ID: 14066
• mRNA Refseq: NM_010171
• Protein Refseq: NP_034301
• UniProt ID: P20352