Recombinant Mouse F11 Protein, MYC/DDK-tagged

• Cat.No.: F11-439M
• Product Overview: Purified recombinant protein of full-length mouse coagulation factor XI (F11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 69.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: F11 coagulation factor XI [ Mus musculus (house mouse) ]
• Official Symbol: F11
• Synonyms: F11; coagulation factor XI; FXI; PTA; Cf11; AI503996; 1600027G01Rik; coagulation factor XI; plasma thromboplastin antecedent; EC 3.4.21.27
• Gene ID: 109821
• mRNA Refseq: NM_028066
• Protein Refseq: NP_082342
• UniProt ID: Q91Y47